We’ll start with the headliner: the BIO-tract peral, which packs the equivalent of 75 billion CFUs into one tiny, filler-free, 5-billion CFUs pearl. The trick is in protecting those 5 billion CFUs over an 8 to 10-hour period, so they bypass your acidic stomach and reach your intestinal tract, alive and well, allowing you to experience the full and multitudinous benefits of plentiful and beneficial gut bacteria.
Probiotics have been consumed by humans in one form or another for over 100 years, with a good safety record generally. A Finnish epidemiological study has shown no increase in Lactobacillus infections in healthy individuals in areas with documented large rises of use of Lactobacillus-containing products [Saxelin et al. 1996]. Probiotic supplementation has been studied in healthy volunteers, and the data suggest that several probiotic strains may enhance nonspecific immune responses, but the effects on adaptive cellular and humoral immune responses appear to be negligible [Borchers et al. 2009].
Mindy Weisberger is a senior writer for Live Science covering general science topics, especially those relating to brains, bodies, and behaviors in humans and other animals — living and extinct. Mindy studied filmmaking at Columbia University; her videos about dinosaurs, biodiversity, human origins, evolution, and astrophysics appear in the American Museum of Natural History, on YouTube, and in museums and science centers worldwide. Follow Mindy on Twitter.
A 2017 survey of cancer patients showed that more than 80 percent were taking some sort of dietary supplement, vitamin, mineral, or herb to treat digestive issues they were experiencing due to chemotherapy. Researchers noted that while supplements can be beneficial in some cases, they can also change the metabolism of anti-cancer drugs, or lead to life-threatening conditions like sepsis because of the patient’s compromised immune system.
Adding probiotics to your diet can be overwhelming. Besides picking a brand, you'll also have to consider what type of formula you prefer. Probiotics can also be packed into powder, such as this one from Garden of Life. You mix one scoop (one-third teaspoon) of it with water or juice to make one serving. Three servings a day are recommended, though the manufacturer suggests starting with one and gradually increasing the amount.
Probiotics are live bacteria that are present in yogurt, other fermented foods, and in pills. They are promoted as a benefit to the human digestive system. Normally you have trillions upon trillions of bacteria within the colon. Normally we ingest bacteria every time we swallow. Many of these swallowed bacteria may be beneficial while most are simply innocuous and cause no problems. The question for everyone who takes a probiotic much beyond yogurt is whether they really are a health benefit. Here is what we know medically about probiotics.
Proponents claim that probiotics (meaning “for life,” as opposed to antibiotics) confer health benefits primarily by rebalancing the normal microflora in the large intestine (colon). There are many general types of bacteria used as probiotics (two common ones are Lactobacillus and Bifidobacterium), and many different species as well as strains within species. They have different physiological effects—and thus possibly different health benefits (as well as possible risks). Some yeasts, such as Saccharmyces, can also act as probiotics.
The newest trend in probiotics is customized formulations that are said to be based on your unique microbiome needs. Companies develop them after testing your stool sample for different microbes, and then selecting probiotics they say you lack in your gut. “While it may be a step in the right direction, the science and technology have a long way to go before this is a viable option,” says Dr. Rawls.
Yes! Beneficial yeast is a probiotic, defined as a microorganism that supports human wellness. (Probiotic means “for life.”) Saccharomyces boulardii is a remarkable yeast that can significantly support your whole internal ecosystem. It helps reduce problematic yeasts, such as Candida, and replenishes healthy gut flora.* While many probiotic supplements only deliver friendly bacteria without yeast, Probiotic All-Flora contains 5 billion CFU of beneficial yeast for complete support.

When it comes to probiotics, it appears that 10 billion live "friendly" bacteria is the magic dose, Dr. Novey says. That number may sound like a lot, but that’s about how many are in an eight-ounce carton of yogurt. (Check the expiration date, Novey notes: The further away the date, the more live bacteria the yogurt is likely to contain.) The probiotic supplements you buy in the health food store probably contain about 10 billion live bacteria per capsule as well. However, according to Novey it’s better to get your daily intake of probiotics from yogurt and other fermented foods than from pills or capsules. For example, yogurt also provides calcium, a much-needed nutrient. “Capsules are better when you need to recover your colon from having taken antibiotics,” he says.
What’s more, your bacterial makeup does more than just boost or bully your immune system; the existence of good and bad bacteria affect your mood and energy levels, relieve (or contribute to) a sensitive stomach (including lactose intolerance and irritable bowel syndrome/IBS), affect your mood, and even support (or hinder) a healthy body weight. (Fascinating fact: Scientists can predict weight with 90% accuracy based on your gut’s bacterial makeup, but only with 58% accuracy based on your genes. Bacteria counts!)
What’s more, your bacterial makeup does more than just boost or bully your immune system; the existence of good and bad bacteria affect your mood and energy levels, relieve (or contribute to) a sensitive stomach (including lactose intolerance and irritable bowel syndrome/IBS), affect your mood, and even support (or hinder) a healthy body weight. (Fascinating fact: Scientists can predict weight with 90% accuracy based on your gut’s bacterial makeup, but only with 58% accuracy based on your genes. Bacteria counts!)
Hi Joan, it’s possible, but not ideal because most pill form probiotic supplements are designed to be protected from stomach acid until the capsule reaches the intestines. It’s impossible to say how many probiotic microorganisms would survive by taking them this way, but certainly less than if you swallow the pills. I would recommend trying a probiotic gummy product or some other probiotic that comes in something other than pill form rather than opening up the capsules.

Premature babies are at risk for this serious disease. Tissue in the intestines starts to die. The intestines get inflamed and a hole can form. Recent studies show that using Lactobacillus rhamnosus GG with the supplement bovine lactoferrin can help keep it under control. Bifidobacterium infantis combined with Lactobacillus acidophilus may also help stave off this problem in sick newborns.


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Infectious diarrhea in both adults and children may be shortened by the use of probiotics [Allen et al. 2004]. The duration of symptoms is decreased by about 30 hours as suggested by a systematic review of trials in active infectious diarrhea. In this Cochrane review, 23 studies including almost 2000 participants (352 of which were adults), it was concluded that probiotics reduced the risk of persistent diarrhea compared with placebo or no probiotics at 3 days with a RR of 0.66 (95% CI 0.55–0.77) [Allen et al. 2004]. The majority (18 out of 23 studies) of the probiotics tested were LABs with two studies using S. boulardii.


Thirdly, the probiotic candidate must be a taxonomically defined microbe or combination of microbes (genus, species, and strain level). It is commonly admitted that most effects of probiotics are strain-specific and cannot be extended to other probiotics of the same genus or species.[113] This calls for a precise identification of the strain, i.e. genotypic and phenotypic characterization of the tested microorganism.[18]
B. longum is one of the first types of bacteria to colonize our bodies at birth. These important microorganisms ferment sugars into lactic acid, helping to stabilize the acidity of the GI tract and inhibit growth of harmful bacteria. For a group of adults prone to constipation, taking a mix of B. longum BB536 with milk or yogurt for two weeks increased bowel movements [1].
That’s why adding probiotics and prebiotics to your diet provide the best possible outcome from a bacterial perspective. It isn’t always easy to eat naturally prebiotic-enriched foods, however, because they are often distasteful to eat in quantity. Would you enjoy eating several cups of raw onion or garlic every day? Probably not. Other foods that contain prebiotic fiber, such as bread and bananas, are high in calories. Consuming hundreds of calories of these foods every day is counterproductive if you’re trying to lose weight.
Future studies should address many of the remaining questions related to the basic knowledge of probiotics, such as the composition of human intestinal flora, viability and fecal recovery rates, physiological and immunological effects. Furthermore, most optimal doses, duration of treatment, comparison of different strains and different probiotics, single versus combination probiotics, combination of probiotics with prebiotics, efficacy of various probiotics in different disease states, and safety of probiotics in debilitated patients or in patients with compromised gut epithelial integrity need to be evaluated.
There have been a multitude of recent studies indicating that the best probiotic supplement should definitely include this beneficial strain of bacteria. In addition to its digestion-boosting benefits, Saccharomyces boulardii has powerful antimicrobial and antitoxin effects, which can help block the growth of bacteria and parasites while also flushing out harmful toxins. (4)
Probiotics are generally considered safe8 for most healthy people, but may cause gastrointestinal discomfort (abdominal tenderness, pain, gas, and/or diarrhea) if intake exceeds individual needs. People with certain health conditions like suppressed immunity or sensitivity to probiotics may experience more severe side effects9. Probiotics can also interact with some medications. Please consult your doctor before starting any new supplement.
Adding probiotics to your diet can be overwhelming. Besides picking a brand, you'll also have to consider what type of formula you prefer. Probiotics can also be packed into powder, such as this one from Garden of Life. You mix one scoop (one-third teaspoon) of it with water or juice to make one serving. Three servings a day are recommended, though the manufacturer suggests starting with one and gradually increasing the amount.
^ Shane AL, Cabana MD, Vidry S, Merenstein D, Hummelen R, Ellis CL, Heimbach JT, Hempel S, Lynch SV, Sanders ME, et al. (2010). ": Guide to designing, conducting, publishing and communicating results of clinical studies involving probiotic applications in human participants". Gut Microbes. 1 (4): 243–253. doi:10.4161/gmic.1.4.12707. PMC 3023606. PMID 21327031.

Hi Joan, it’s possible, but not ideal because most pill form probiotic supplements are designed to be protected from stomach acid until the capsule reaches the intestines. It’s impossible to say how many probiotic microorganisms would survive by taking them this way, but certainly less than if you swallow the pills. I would recommend trying a probiotic gummy product or some other probiotic that comes in something other than pill form rather than opening up the capsules.


From Lactobacillus acidophilus to Bacillus Coagulans, the BlueBiotics blend is a veritable list of the most researched and proven probiotic bacteria known to science. And recent advances on the blend have made it the only full-spectrum probiotic supplement on the market, as it contains strains which are typically not available to the general public (Bacillus Coagulans and S. boulardii). The CFU count alone is remarkable enough, leaving most comparable spectrums in the dust… HOWEVER even more surprisingly our tests showed that a whopping 98% of the probiotic colonies in BlueBiotics were still alive, making this BY FAR the most effective probiotic supplement that we have ever reviewed. Also, because of the diverse pool of strains in BlueBiotics, users have reported a wide variety of benefits from weight loss, to increased energy, improved digestive health and cognitive function. Many of our staff switched to these probiotics, as well as myself and my family.
There have been a multitude of recent studies indicating that the best probiotic supplement should definitely include this beneficial strain of bacteria. In addition to its digestion-boosting benefits, Saccharomyces boulardii has powerful antimicrobial and antitoxin effects, which can help block the growth of bacteria and parasites while also flushing out harmful toxins. (4)
If you have annoying tummy troubles... Allow your predominant symptoms to guide you. Bloated and constipated? Look for lactobacillus acidophilus or lactobacillus casei, which help restore gut flora. Can't stop going number two? Types with saccharomyces boulardii can ease antibiotic-associated diarrhea and even prevent extreme cases caused by infections.
Supplements: dietary probiotic supplements -- which are available in capsules, tablets, powders and liquid extracts -- each contain a specific type of probiotic. These products are available at health food and natural food stores, vitamin shops, and other stores. As an example, one commonly used supplement is acidophilus, which is available from several supplement manufacturers.
The good guys in your intestinal tract support the production of hundreds of nervous system chemicals that regulate your moods. Indeed, almost 95% of your body’s serotonin—the happiness chemical also found in the brain—is manufactured in your gut, so replenishing them often is one of the best things you can do to support healthy emotional function.

The best case for probiotic therapy has been in the treatment of diarrhea. Controlled trials have shown that Lactobacillus GG can shorten the course of infectious diarrhea in infants and children (but not adults). Although studies are limited and data are inconsistent, two large reviews, taken together, suggest that probiotics reduce antibiotic-associated diarrhea by 60%, when compared with a placebo.
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Microbes are tiny organisms (bacteria, viruses, parasites, or fungi) -- so tiny that millions can fit into the eye of a needle -- that are so powerful that an imbalance in the body is related to numerous diseases. These microorganisms can be found in almost every part of the human body, living on the skin, in the nose, and in the gut. There are trillions of these microorganisms in our bodies. They outnumber human cells by 10 to one, but due to their small size, they only make up 1%-3% of a body's total mass.
While it produces no sensations for you to detect, an entire natural ecosystem is living in your digestive tract. In the average person, 100 trillion microorganisms reside in the healthy bowel with more than 500 different species accounted for in their vast numbers. Some of these bacteria are harmful and can produce symptoms of illness. However, there are healthy good bacteria present to keep them in check. Among these bacteria are Lactobacillus acidophilus and bifidobacterium or bifidus. In some people, levels of the healthy bacteria are below the norm. Low levels can be caused by taking antibiotics, which kill good bacteria. This allows harmful bacteria to reproduce rapidly and cause various symptoms. Probiotic rich foods and dietary supplements may help to re-balance the gut. They add live cultured good bacteria to the stomach. In addition, the healthy bacteria may assist with digestion, strengthen the immune system and help nutrients become absorbed more efficiently.

Lactobacillus predominantly live in your small bowel (the portion of your gut that follows the stomach). Probiotics containing Lactobacillus sp. help to repopulate the small intestine with friendly organisms that aid in supporting digestion and immune function. The most beneficial are L. acidophilus, L. plantarum, and L. paracasei. One study found Lactobacillus acidophilus could reduce gut inflammation. L. rhamnosus helps increase GABA expression (an inhibitory neurotransmitter that helps you feel relaxed) in the brain, resulting in lower anxiety and depression-related behavior. Another found that a combination of Lactobacillus and Bifidobacteria (which we'll talk about next) improved symptoms of bloating in patients with functional bowel disorders, and yet another found that when people took the Lactobacillus rhamnosus GG strain, it significantly reduced the risk for antibiotic-associated diarrhea.
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