L. casei also made headlines when a study found it beneficial in relieving anxiety. The randomized, double-blind, placebo-controlled pilot study found supplementation with 24 billion units of the L. casei strain Shirota led to a rise in probiotics lactobacillus and bifidobacterium, as well as a significant decrease in symptoms of anxiety and depression [2].
If you have an immune system problem or another serious health condition, you may have a greater chance of issues. Some reports have linked probiotics to serious infections and other side effects. The people most likely to have trouble are those with immune system problems, people who've had surgery, and others who are critically ill. Don't take probiotics if you have any of those issues.
The GI tract plays an important role as an interface between the host and the environment. It is colonized by about 10 trillion microbes of many different species, amounting to 1–2 kg in weight [O’Hara and Shanahan, 2006]. Only a minority (300–500) of these species can be cultured in vitro and studied [O’Hara and Shanahan, 2006]. Intestinal epithelial cells have the capacity to distinguish pathogenic from nonpathogenic bacteria on the basis of their invasiveness and the presence of flagella, although the exact mechanisms that allow them to do this have not been elucidated fully [Borchers et al. 2009].
Probi is continuously thriving to develop and investigate new possible indications where probiotics may have positive and efficient effects to improve health. We are science-driven, and investigate new possibilities to find the Next Generation Probiotics. This concept involves new bacterial strains that has never before been cultivated and used for health-purposes. 

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Even if some of the bacteria in a probiotic managed to survive and propagate in the intestine, there would likely be far too few of them to dramatically alter the overall composition of one's internal ecosystem. Whereas the human gut contains tens of trillions of bacteria, there are only between 100 million and a few hundred billion bacteria in a typical serving of yogurt or a microbe-filled pill. Last year a team of scientists at the University of Copenhagen published a review of seven randomized, placebo-controlled trials (the most scientifically rigorous types of studies researchers know how to conduct) investigating whether probiotic supplements—including biscuits, milk-based drinks and capsules—change the diversity of bacteria in fecal samples. Only one study—of 34 healthy volunteers—found a statistically significant change, and there was no indication that it provided a clinical benefit. “A probiotic is still just a drop in a bucket,” says Shira Doron, an infectious disease expert at Tufts Medical Center. “The gut always has orders of magnitude more microbes.”

Medications (especially antibiotics), stress, diet and other factors can alter the ratio of good to bad bacteria in your gut, causing infection and disease. This happens more often than you might think: antibiotics are one of the most prescribed medications in Canada and the US (and often prescribed unnecessarily… but that’s another story) (3;4). They’re important and effective in killing infection-causing bacteria, but they often end up killing a lot of good bacteria, upsetting that important balance and giving dangerous Clostridium difficile bacteria a chance to cause severe diarrhea and other bowel diseases, sometimes with fatal results (5).

The newest trend in probiotics is customized formulations that are said to be based on your unique microbiome needs. Companies develop them after testing your stool sample for different microbes, and then selecting probiotics they say you lack in your gut. “While it may be a step in the right direction, the science and technology have a long way to go before this is a viable option,” says Dr. Rawls.
Kimchi: This fermented vegetable is made from Chinese cabbage (beachu), radish, green onion, red pepper powder, garlic, ginger, and fermented seafood (jeotgal). Many bacteria have been found to be present and can include any of the following: Leuconostoc mesenteroides and Lactobacillus plantarum, L. mesenteroides, L. citreum, L. gasicomitatum, L. brevis, L. curvatus, L. plantarum, L. sakei, L. lactis, Pediococcus pentosaceus, Weissella confusa, and W. koreensis. A recent review linked the health benefits of kimchi to anticancer, antiobesity, anticonstipation, colon health promotion, cholesterol reduction, antioxidative and antiaging properties, brain health promotion, immune promotion, and skin health promotion.
In 2015, the global retail market value for probiotics was US$41 billion, including sales of probiotic supplements, fermented milk products, and yogurt, which alone accounted for 75% of total consumption.[42] Innovation in probiotic products in 2015 was mainly from supplements, which produced US$4 billion and was projected to grow 37% globally by 2020.[42] Consumption of yogurt products in China has increased by 20% per year since 2014.[43] 

^ Cuello-Garcia CA, Brożek JL, Fiocchi A, Pawankar R, Yepes-Nuñez JJ, Terracciano L, Gandhi S, Agarwal A, Zhang Y, Schünemann HJ (2015). "Probiotics for the prevention of allergy: A systematic review and meta-analysis of randomized controlled trials". J. Allergy Clin. Immunol. (Systematic review & meta-analysis). 136 (4): 952–61. doi:10.1016/j.jaci.2015.04.031. PMID 26044853.

"The name itself is derived from the Latin 'pro-' meaning 'for' and the Greek '-biotic' meaning 'life,'" explains Jeannel Astarita, skincare expert and founder of Just Ageless NYC Wellness and Medspa. "Probiotics are the helpful bacteria that live primarily in your gut and play a crucial role in your overall health by fighting pathogens and yeast that lead to a weakened immune system."
Now researchers are finding evidence that the effects of bacteria in the gastrointestinal (GI) system send signals to the central nervous system, linking the gut with the brain. This could account for some known connections between GI illness and mental illness. For example, a higher-than-average number of people with irritable bowel syndrome also develop depression and anxiety.
"In fact," she continues, "80% of immune system cells are found in the gut. In addition to the well-known GI benefits of minimizing bloat, gas, constipation, and diarrhea, probiotics aid in digestion by extracting nutrients, helping your body absorb minerals, produce vitamins, and make brain chemicals, including over 30 neurotransmitters along with mood-enhancing serotonin. A healthy person has over 100 trillion microbes, generally a five to one ratio of helpful to harmful."
While the logic behind probiotics might seem sound, it is clear that we have a long way to go before understanding the complexity of the microbiota and the effects—both good and bad—that probiotics might have. All individuals have a unique gut microbiome, and the effects of different bacteria on different people are likely to be highly variable; as such, probiotic use might even need to be personalised for optimal benefits. Commercially available products might not contain the correct strains or quantities of bacteria to provide benefits, and most probiotic supplements contain only single strains, vastly oversimplifying the complexity of the microbiota. While taking a supplement for improved health is certainly an attractive prospect, those looking to aid their gut microbiota might be better served by consuming a healthy, varied diet. In the meantime, rigorous clinical trials are needed to substantiate potential health benefits and to confirm whether probiotics are elixirs or just empty promises.
Even if a product's label shows it has the jackpot billion CFUs, they may not all be present when you swallow the pill. That's because probiotics are living organisms; they can die when it's too hot (if the label says to refrigerate, do it), and if they swelter too long in transit or on a shelf, the bacteria may be DOA. Meaning, if you're out running errands, pick up your probiotic supplements last, as they may lose some of their potency if left in a hot car. The good bugs also decay over time, so when you're shopping, choose the container with the furthest-out expiration date.
But put down your kombucha, friends, because science has not quite proven that's the case yet, says Robert Hutkins, Ph.D., a scientist at the Nebraska Food for Health Center in Lincoln. Of the hundreds of identified probiotic strains, studies have only ID'd a handful that are helpful in treating specific conditions. And there's no evidence they have much effect on the microbiota of healthy individuals, per recent studies.
The Bifidobacteria (Bifidus) predominantly live in your colon or large intestine. They produce the very important short-chain fatty acid butyrate, which supplies energy to your colon cells to keep them functioning optimally. But butyrate also gets absorbed by the body, regulating a variety of metabolic processes, including your sensitivity to the hormone insulin (which regulates blood sugar) and even memory formation in the brain. The most beneficial of these are B. lactis and B. longum. Research shows the benefits for Bifidobacteria include reducing inflammatory bowel disease and several cancers, especially colon cancer. Another study showed that a specific strain of Bifidobacterium lactis helped control body fat mass and reduced waist circumference and food intake.
We have used probiotics and prebiotic on horses since 1986, notice many benefits such less colic, healthier foals, better hoofs, helps with stomach ulcers, as well as cost savings. A hard keeping horse generally does not absorb the nutrients well the probiotics clearly improved that. Also dogs can benefit as well as any other animal not living in its natural environment. Our dogs have very little gas and no doggy smell. 16 years ago I found a blend that has worked for me since then I have not lost a day to colds, flu my issue of gas, bloat greatly reduced, my craving for sweets greatly reduced
No matter how many superfoods you eat, your body won’t be able to benefit from them if your gut environment isn’t teeming with healthy bacteria. You see, enzymes and digestive bacteria help to break down the food you eat into molecules that make their way into your bloodstream to nourish your body. Inadequate or unbalanced microbial populations in the gut can derail this process and can even lead to malabsorption of critical nutrients. 
Rachel Allen is a writer at Hyperbiotics who's absolutely obsessed with learning about how our bodies work. She's fascinated by the latest research on bacteria and the role they play in health, and loves to help others learn about how probiotics can help the body get back in balance. For more ideas on how you can benefit from the power of probiotics and live healthier days, be sure to subscribe to our newsletter. To learn more about how a healthy microbiome can enrich your life, subscribe to our newsletter.
The Golive Berry Probiotic and Prebiotic Supplement Blend is perfect for tossing in your bag or keeping in your desk. Each packet includes 15 billion CFUs and 15 different probiotic strains. It also has a soluble fiber prebiotic to promote the growth of good bacteria in your body. Each packet contains 30 calories and comes in five flavors including pomegranate, melon cucumber, citrus blueberry, and a flavorless option. It can be mixed in any hot or cold drink, but we recommend tossing the flavored packet into a bottle of water. You’ll get 10 packets in each order.
Once you have identified the right strain or strains, it's important to find a product that provides a dose that's been shown to be effective, and that contains it's labeled dose (ConsumerLab.com tests have found some probiotic supplements to contain less than half the amount of organisms claimed on the label!) To get test results for popular products, plus additional tips for choosing a probiotic supplement, see the Probiotic Supplements Review >>

Officials in the E.U., where supplements are more heavily regulated than in the U.S., haven't authorized the use of the word probiotic to back any health claim. The only approved use related to microorganisms is "live yogurt cultures and improved lactose digestion." It can all feel like, well, a punch to the gut. So we asked scientists at the forefront of probiotic research to help us separate fact from hype, and pros...from cons. Here's what you need to know.