Unlike MegaFood, the Renew Life label’s cold-storage recommendation is printed so small we nearly missed it (and it didn’t ship with a cold pack). If a probiotic requires refrigeration, be vigilant when buying it — the retailer that stores it or the company that ships it should keep it refrigerated until it gets to you. Otherwise, some of its potency might diminish in storage or transit.

As for probiotics’ ability to improve digestive symptoms, the answer is possibly. Probiotic capsules seem to help most when they’re used short-term for acute GI upset (diarrhea, stomach cramps) from eating contaminated food, like a batch of chicken salad that sat out for too long, for example, Dr. Rawls says. They may also help protect your microflora while taking antibiotics, which kill off good bacteria along with the bad, or if you contract C. difficile, a dangerous bacterial infection that causes diarrhea and inflammation of the gut.


Probiotics may produce their effects with viable as well as nonviable bacteria, suggesting that metabolic or secreted factors or structural or cellular components may mediate their immunomodulatory activities [Borchers et al. 2009]. Furthermore, several experiments indicate that the ability to induce secretion of various cytokines is mediated by and large by cell wall components [Borchers et al. 2009].

This is also known as S. boulardii and is the only yeast probiotic. Some studies have shown that it is effective in preventing and treating diarrhea associated with the use of antibiotics and traveler's diarrhea. It has also been reported to prevent the reoccurrence of C. difficile, to treat acne, and to reduce side effects of treatment for H. pylori.

“Since brain fog, weight gain, and skin problems can stem from poor gut health, it was important for me to have a probiotic I can recommend to my patients,” says Will Cole, DC, a functional medicine practitioner in Pittsburgh. “I developed this probiotic with 100 billion CFUs per capsule and four strains of beneficial bacteria, including the extensively studied HN019 strain of B. lactis.” Bowel issues and brain fog are two of the fibromyalgia symptoms you might be ignoring.
Probiotics help tip the balance back in favor of the good bacteria. In doing so, they may provide some relief if you have irritable bowel syndrome (IBS), ulcerative colitis, acute infectious diarrhea, and diarrhea associated with antibiotic use or Clostridium difficile (C.diff) infection. They also can boost your immunity, fight inflammation and potentially have beneficial effects on cholesterol.
I did the “milk test” on these New Rythm probiotics, along with Culturelle I had purchased in 2 different states (TX & MA, as I was traveling); my mother’s CVS brand acidophilus; and one “control” cup with milk only (so, 5 cups total in my experiment). The New Rythm became a solid yogurt consistency, while the other 4 remained liquids. I did the experiment twice, just to be sure of the results. I could not believe it!!! New Rhythm is my brand, hands down!!! I also would like to mention that my product usually arrives the day after it ships. So it will take a few days to ship when I select standard shipping, which is to be expected, but it doesn’t stay in transit long which is ideal for preserving the living cultures.
‡The comparison price represents an estimated selling price of the same or similar product. Where identical products/combinations are not available we may compare to similar products or combinations. Actual sales may not have been made at the “Compare at” price in all trade areas, and the “Compare at” price may not represent the average or prevailing market price at any particular time. The “Compare at” price may not have been in effect during the past 90 days.
Probiotics are generally considered safe8 for most healthy people, but may cause gastrointestinal discomfort (abdominal tenderness, pain, gas, and/or diarrhea) if intake exceeds individual needs. People with certain health conditions like suppressed immunity or sensitivity to probiotics may experience more severe side effects9. Probiotics can also interact with some medications. Please consult your doctor before starting any new supplement. 

Garden of Life RAW Probiotics are some of the most popular out there – and for good reason. Let’s start with the basics: You’ll get 85 billion CFUs and 31 to 33 probiotic strains out of your daily, whole-food, gluten-free, soy-free probiotic, which helps support the immune system, a healthy thyroid, nutrient absorption, digestive function, and a healthy microbial balance.
^ Jump up to: a b c "Scientific Opinion on the substantiation of a health claim related to a combination of Bifidobacterium longum LA 101, Lactobacillus helveticus LA 102, Lactococcus lactis LA 103 and Streptococcus thermophillus LA 104 and reducing intestinal discomfort pursuant to Article 13(5) of Regulation (EC) No 1924/2006 (example, search EFSA for other opinion reports on probiotics". EFSA Journal. 11 (2): 3085. 2013. doi:10.2903/j.efsa.2013.3085.
“It is quite difficult to choose a solid top pick for probiotics because different strains have been shown to help different clinical issues,” says Rachel Fine, MS, RD, CSSD, a dietitian in New York City. “However, this supplement is a great option, with 50 billion strains.” It’s one of the best probiotics for women and supports vaginal, digestive, and immune system health. “It is best to choose a product that is well within its expiration date to ensure a higher number of viable cells,” advises Fine.
No matter how many superfoods you eat, your body won’t be able to benefit from them if your gut environment isn’t teeming with healthy bacteria. You see, enzymes and digestive bacteria help to break down the food you eat into molecules that make their way into your bloodstream to nourish your body. Inadequate or unbalanced microbial populations in the gut can derail this process and can even lead to malabsorption of critical nutrients. 
The newest trend in probiotics is customized formulations that are said to be based on your unique microbiome needs. Companies develop them after testing your stool sample for different microbes, and then selecting probiotics they say you lack in your gut. “While it may be a step in the right direction, the science and technology have a long way to go before this is a viable option,” says Dr. Rawls.
There’s preliminary evidence that some probiotics are helpful in preventing diarrhea caused by infections and antibiotics and in improving symptoms of irritable bowel syndrome, but more needs to be learned. We still don’t know which probiotics are helpful and which are not. We also don’t know how much of the probiotic people would have to take or who would most likely benefit from taking probiotics. Even for the conditions that have been studied the most, researchers are still working toward finding the answers to these questions.
Probiotics are found in everything from chocolate and pickles to hand lotion and baby formula, and millions of people buy probiotic supplements to boost digestive health. But new research suggests they might not be as effective as we think. Through a series of experiments looking inside the human gut, researchers show that many people's digestive tracts prevent standard probiotics from successfully colonizing them. Furthermore, taking probiotics to counterbalance antibiotics could delay the return of normal gut bacteria and gut gene expression to their naïve state. The research publishes as two back-to-back papers on September 6 in the journal Cell.
However, it’s not just digestive woes that probiotics can help address. A clinical case series followed 300 patients who took a probiotic mixture of L. acidophilus and L. bulgaricus. They documented that 80% of acne patients had some degree of clinical improvement, particularly effective in inflammatory acne. Later, an Italian study involving 40 patients found L. acidophilus and B. bifidum supplementation produced better clinical outcomes in acne as well as better tolerance and compliance with antibiotics [2].
What is the difference between prebiotics and probiotics? Prebiotics and probiotics work together to encourage the growth of beneficial bacteria that can improve digestion and support the immune system. Both prebiotics and probiotics occur naturally in many foods. Here, learn more about the differences between them, their benefits, and how to incorporate them into the diet. Read now
Some probiotics are suggested as a possible treatment for various forms of gastroenteritis,[91] and a Cochrane Collaboration meta-analysis on the use of probiotics to treat acute infectious diarrhea based on a comprehensive review of medical literature through 2010 (35 relevant studies, >4500 participants) reported that use of any of the various tested probiotic formulations appeared to reduce the duration of diarrhea by a mean of 25 hours (vs. control groups, 95% confidence interval, 16–34 hours), also noting, however, that "the differences between the studies may be related to other unmeasured and unexplored environmental and host factors" and that further research was needed to confirm reported benefits.[92][93]
Though rates of serious lung issues have been dropping among men in the Western world, they're still a major concern, with over three million men affected by ongoing respiratory conditions.1 While steroids and antibiotics are the go-to treatments for these conditions, they often fail to address the underlying issue, and they destroy bacteria indiscriminately, creating conditions in which undesirable bacteria can thrive.
The prebiotic comes before and helps the probiotic, and then the two can combine to have a synergistic effect, known as synbiotics. A prebiotic is actually a nondigestible carbohydrate that acts as food for the probiotics and bacteria in your gut. The definition of the effect of prebiotics is the selective stimulation of growth and/or activity(ies) of one or a limited number of microbial genus(era)/species in the gut microbiota that confer(s) health benefits to the host. The health benefits have been suggested to include acting as a remedy for gastrointestinal (GI) complications such as enteritis, constipation, and irritable bowel disease; prevention and treatment of various cancers; decreasing allergic inflammation; treatment of nonalcoholic fatty liver disease (NAFLD), and fighting immune deficiency diseases. There has also been research showing that the dietary intake of particular food products with a prebiotic effect has been shown, especially in adolescents, but also tentatively in postmenopausal women, to increase calcium absorption as well as bone calcium accretion and bone mineral density. The benefits for obesity and type 2 diabetes are growing as recent data, both from experimental models and from human studies, have shown particular food products with prebiotics have influences on energy homeostasis, satiety regulation, and body weight gain.
What’s more, your bacterial makeup does more than just boost or bully your immune system; the existence of good and bad bacteria affect your mood and energy levels, relieve (or contribute to) a sensitive stomach (including lactose intolerance and irritable bowel syndrome/IBS), affect your mood, and even support (or hinder) a healthy body weight. (Fascinating fact: Scientists can predict weight with 90% accuracy based on your gut’s bacterial makeup, but only with 58% accuracy based on your genes. Bacteria counts!)
The side effects of antibiotic use are often not trivial. Many people experience discomfort and a change in bowel habits, but some experience more severe infections, such as opportunistic colonization of the gut with bacteria such as Clostridium difficile (C.diff), which affected half a million Americans in 2015 and was directly responsible for at least 15,000 deaths.
Chronic inflammation contributes to nearly every disease imaginable, and it doesn’t do your gut any favors. Studies connect inflammation with everything from leaky gut to weight gain. Those are among the many reasons to add cold-water fish and other omega-3-rich foods to your diet. The two primary omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are important anti-inflammatory promoters in the body often deficient in the American diet. Along with these foods, take one to four 1,000-milligram softgels daily with meals to enhance their absorption.
“It is quite difficult to choose a solid top pick for probiotics because different strains have been shown to help different clinical issues,” says Rachel Fine, MS, RD, CSSD, a dietitian in New York City. “However, this supplement is a great option, with 50 billion strains.” It’s one of the best probiotics for women and supports vaginal, digestive, and immune system health. “It is best to choose a product that is well within its expiration date to ensure a higher number of viable cells,” advises Fine.
Yes! Beneficial yeast is a probiotic, defined as a microorganism that supports human wellness. (Probiotic means “for life.”) Saccharomyces boulardii is a remarkable yeast that can significantly support your whole internal ecosystem. It helps reduce problematic yeasts, such as Candida, and replenishes healthy gut flora.* While many probiotic supplements only deliver friendly bacteria without yeast, Probiotic All-Flora contains 5 billion CFU of beneficial yeast for complete support.

Make sure to keep probiotics away from moisture and heat, which can kill off some of the microbes. I recommend taking them on an empty stomach, ideally right when you wake up. You should always store supplements in a cool, dark place. Most strains of probiotics are fragile and should be protected from heat, so refrigeration is ideal. I recommend the probiotic Gut Instinct from HUM Nutrition for transparency and high quality.


It’s not just about vanity! Your skin is your largest organ, and it protects your body from countless external threats. But, what many people don’t realize is that your skin is an important reflection of your internal health. Skin problems can result from nutritional and hormonal imbalances, as well as immune system disruptions, all issues that begin in the gut.
In 1920, Rettger and Cheplin reported that Metchnikoff's "Bulgarian Bacillus", later called Lactobacillus delbrueckii subsp. bulgaricus, could not live in the human intestine.[59] They conducted experiments involving rats and humans volunteers, feeding them with Lactobacillus acidophilus. They observed changes in composition of fecal microbiota, which they described as "transformation of the intestinal flora".[59] Rettger further explored the possibilities of L. acidophilus, and reasoned that bacteria originating from the gut were more likely to produce the desired effect in this environment. In 1935 certain strains of L. acidophilus were found very active when implanted in the human digestive tract.[60] Trials were carried out using this organism, and encouraging results were obtained, especially in the relief of chronic constipation.[citation needed]
Undaunted, researchers looked into whether probiotics might be beneficial in a host of disorders, even when the connection to gut health and the microbiome was tenuous. Reviews show that there is insufficient evidence to recommend their use to treat or prevent eczema, preterm labor, gestational diabetes, bacterial vaginosis, allergic diseases or urinary tract infections. 

Probiotics: Health benefits, facts, and research Every human on the planet has microbes living in their body. While bacteria get a bad reputation, many can promote good health. Probiotics are a type of 'good bacteria' that provide health benefits for the host. The health benefits of probiotics include treatment of diarrhea and irritable bowel syndrome. Read now

Many studies have shown that probiotics reduce diarrhea associated with taking antibiotics in both adults and children. In fact, it is common for physicians and pharmacists to recommend eating a probiotic-fortified yogurt every day during a course of antibiotics to prevent diarrhea. More research is needed to determine which probiotics are associated with the greatest effect for specific antibiotics. 

She totally did, but you may have noticed that you don't see those yogurt commercials anymore. That’s because in 2010, the Federal Trade Commission in conjunction with 39 states' attorney generals banned those ads, finding that the Dannon Company had no scientific evidence to back up their claims,. Dannon had to pay $21 million to resolve the associated investigations.

Fecal microbiota transplants (FMT), or "poop transplants," can treat a type of gut disorder with an infusion of diverse bacteria from a healthy digestive system, distilled from a donor's poop. This helps to correct imbalances of microbial diversity when the gut microbiome is dominated by the bacteria Clostridium difficile (C. diff), which can lead to serious gut disorders. 
The European Food Safety Authority has rejected all petitions by commercial manufacturers for health claims on probiotic products in Europe due to insufficient research, and thus inconclusive proof of effectiveness.[3][44] Occurring over many years, the scientific reviews established that a cause-and-effect relationship had not been sufficiently proven in the products submitted.[44] The European Commission placed a ban on putting the word "probiotic" on the packaging of products because such labeling misleads consumers to believe a health benefit is provided by the product when no scientific proof exists to demonstrate that health effect.[3][45][46][47]
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Because chronic inflammation is at the root of many diseases and health conditions, the fact that probiotics exert this effect in the gut, where 80 percent of the immune system lies, is crucial. The immune-boosting benefits of probiotics seem to be particularly helpful for the quality of life of seniors. Currently, research is underway to test whether probiotics can “reduce inflammation and improve gut immune health in HIV-positive individuals” who haven’t yet undergone treatment.
^ Wu, G. D.; Chen, J.; Hoffmann, C.; Bittinger, K.; Chen, Y.-Y.; Keilbaugh, S. A.; Bewtra, M.; Knights, D.; Walters, W. A.; Knight, R.; Sinha, R.; Gilroy, E.; Gupta, K.; Baldassano, R.; Nessel, L.; Li, H.; Bushman, F. D.; Lewis, J. D. (2011). "Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes". Science. 334 (6052): 105–8. Bibcode:2011Sci...334..105W. doi:10.1126/science.1208344. PMC 3368382. PMID 21885731.
I did the “milk test” on these New Rythm probiotics, along with Culturelle I had purchased in 2 different states (TX & MA, as I was traveling); my mother’s CVS brand acidophilus; and one “control” cup with milk only (so, 5 cups total in my experiment). The New Rythm became a solid yogurt consistency, while the other 4 remained liquids. I did the experiment twice, just to be sure of the results. I could not believe it!!! New Rhythm is my brand, hands down!!! I also would like to mention that my product usually arrives the day after it ships. So it will take a few days to ship when I select standard shipping, which is to be expected, but it doesn’t stay in transit long which is ideal for preserving the living cultures. 

RELATED SUPPLEMENTS: Prebiotics, Lactobacillus Acidophilus, Lactobacillus Bulgaricus, Lactobacillus Rhamnosus, Bifidobacterium Bifidum, Bifidobacterium Infantis, Bifidus Regularis, Lactobacillus Bifidus, Lactobacillus Brevis, Lactobacillus Casei, Lactobacillus Fermentum, Lactobacillus Gasseri, Lactobacillus Lactis, Lactobacillus Plantarum, Bifidobacterium Animalis, Bifidobacterium Lactis, Bifidobacterium Longum, Saccharomyces Boulardii
Dr. Vincent M. Pedre, medical director of Pedre Integrative Health and president of Dr. Pedre Wellness, is a board-certified internist in private practice in New York City since 2004. His philosophy and practices are a blend of both Western and Eastern medical traditions. He is a clinical instructor in medicine at the Mount Sinai School of Medicine and is certified in yoga and medical acupuncture. His unique methodology is best described as integrative or defined by a functional, systems-based approach to health. With his holistic understanding of both sides of the equation, he can help each patient choose the best course of action for their ailments to provide both immediate and long-term relief. His holistic approach incorporates positive, preventive health and wellness lifestyle choices. Dr. Pedre Wellness is a growing wellness platform offering health-enhancing programs along with informative social media and lifestyle products, such as dietary supplements, books, and weight-loss programs.
The National Yogurt Association, who created this seal of approval, requires all yogurt manufacturers to include it on products that meet the standard of having a sufficient number of probiotics. The probiotics in store-bought yogurt need to meet this standard in order to be shelf-stable and reach your body alive. But even then, this standard isn’t all that useful in practice. The number just refers to the total number of live cultures and not the levels for each of those microbes. It’s possible, Taub-Dix says, that a product won’t have high enough levels of a certain probiotic to have any effect.

Because probiotics are taken by mouth, their efficacy depends on how well they can stand up to the very acidic environment of the stomach and gastrointestinal tract. The highest quality probiotics will pass through your stomach still intact and move into the intestines where nutrients are absorbed. This is where probiotics do most of their healing and good work.


Probiotics are found in everything from chocolate and pickles to hand lotion and baby formula, and millions of people buy probiotic supplements to boost digestive health. But new research suggests they might not be as effective as we think. Through a series of experiments looking inside the human gut, researchers show that many people's digestive tracts prevent standard probiotics from successfully colonizing them. Furthermore, taking probiotics to counterbalance antibiotics could delay the return of normal gut bacteria and gut gene expression to their naïve state. The research publishes as two back-to-back papers on September 6 in the journal Cell.
^ Jump up to: a b c d e Goldenberg, Joshua Z.; Lytvyn, Lyubov; Steurich, Justin; Parkin, Patricia; Mahant, Sanjay; Johnston, Bradley C. (2015-12-22). "Probiotics for the prevention of pediatric antibiotic-associated diarrhea". The Cochrane Database of Systematic Reviews (12): CD004827. doi:10.1002/14651858.CD004827.pub4. ISSN 1469-493X. PMC 3374737. PMID 26695080.

There are numerous types of probiotics and each has different characteristics. They may be combined with others or appear on their own in powder, tablet or liquid dietary supplements. At the moment, foods that naturally contain probiotics are not eaten regularly in the UK and supplements are becoming more popular. The most common probiotics include lactobacillus acidophilus and bifidobacterium. These differ as they are made up of different types or strains of bacteria, and are recommended for different clinical conditions. Lactobacillus acidophilus have been clinically shown to lower the incidence of antibiotic-associated diarrhoea and can also result in a shorter length of stay in hospital for some. In order to experience this benefit, a vast quantity of food containing probiotics would need to be consumed. It is therefore easier and more effective to take a recommended probiotic supplement. 
Unfortunately, many commercial brands don’t measure up. They are unstable in stomach acid. Quality control measures aren’t intact, including ensuring supplements have been handled correctly and maintain their freshness. Moisture slipping into probiotic supplements can reduce their efficacy. Companies that use bioshield capsules produce higher quality probiotic supplements that are able to endure the stomach acid, releasing their contents within the small intestine, where a more alkaline environment ensures the survival of the bacteria.
There have been multiple additional studies which link stress to changes in gut bacteria, so there does appear to be some sort of link. But Lebwohl says it’s not enough to recommend widespread use in clinical practice. He referred to these as “hypothesis-generating studies,” which should lead to concrete clinical trials in which the probiotics are tested against a placebo. “These are important studies,” he says. “But it’s premature to call them practice-changing studies.”
Other ingredients: Maltodextrin, hypromellose (capsule), ferment media (organic Saccharomyces cerevisiae, organic gum acacia, organic soy flour, organic molasses, lactic acid bacteria [Lactobacillus acidophilus, Bifidobacterium bifidum and Lactobacillus rhamnosus], bromelain [deactivated] and papain [deactivated]), glycerin, silicon dioxide, microcrystalline cellulose, rice extract and sunflower oil.
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